M-PM2 – Fungal Biosynthesis and Chemodiversity

Time: 1:15 pm - 3:30 pm
Location: Salon D
Chair: Lin Du (NIH, National Cancer Institute) Parallel Session Yi Tang (UCLA) Discovery of New Structures, Enzymes and Functions from Fungal Biosynthetic Pathways Dan Xue (University of South Carolina) Harnessing Bioactivity-led Metabolomics for Natural Products Discovery Targeting A Rare and Severe Cancer Robert Stankey (Terra Bioforge) Directed BGC Cloning Combined with Bacterial and Fungal Expression […]

Younger Members Event – Pinstripes

Time: 6:00 pm - 9:00 pm
Location: Pinstripes
Younger Members Event at Pinstripes.  The Younger Members Event is for students, postdocs, and early career scientists. If you are unsure you fit into these categories or want to know more about this event, please contact skylarcarlson@gmail.com.

S-PM2 – Microbiome/Probiotics Interactions

Time: 1:15 pm - 3:30 pm
Location: Salon D
Chair: Barbara C. Sorkin (NIH Office of Dietary Supplements) Parallel Session Yasmine Belkaid (NIH/NIAID) Microbiome Control of Host Immunity Lois Kwane Kyei (Virginia Tech) Bioassay-Guided Isolation of Pseudochelin A from Marine Egg Mass Microbiome Jakub Piwowarski (Medical University of Warsaw) Revision of Current Concepts of Tannins Impact on Gastrointestinal Tract Homeostasis in Piglets George Neuhaus […]

S-PM1 – Old Molecules /New Purposes

Time: 1:15 pm - 3:30 pm
Location: Salon A-C
Chair: Wendy Strangman Parallel Session Patrick Grohar (Children’s Hospital of Philadelphia, University of Pennsylvania) Development of Mithramycin and Analogs as Targeted Therapy for Pediatric Solid Tumors Cole Gannett (Virginia Tech)  Derivatives of the Antimicrobial Natural Product Blasticidin S Enhance its Antibiotic Activity Mark Hamann (Medical University of South Carolina) The Unique Potential of the Platanosides as a […]

Symposium II – NP that Modify Macromolecular Interactions: PPI, RNA-Prot, DNA-Prot etc.

Time: 10:30 am - 12:15 pm
Location: Salon A - D
Chair - Carole Bewley and Barry O'Keefe Anna Mapp (University of Michigan) Writing the Rules for Targeting Dynamic Transcriptional Coactivators with Natural Products Oleg Tsodikov (University of Kentucky)  Structural Insight into Antagonism of Oncogenic Transcription Factors by Mithramycin Analogues Roberto De Guzman (University of Kansas) Bacterial Nanoinjectors as Target for New Antimicrobials

Symposium I – Where Chemistry and Biology Meet

Time: 8:00 am - 10:00 am
Location: Salon A - D
Chair - Carole Bewley and Barry O'Keefe   Jay Keasling (University of California, Berkeley) Production of Supply-Limited Natural Product Therapeutics Using Engineered Yeast Bonnie Bassler (Princeton University) Quorum Sensing Across Domains: From Viruses to Bacteria to Eukaryotes